Transcatheter edge-to-edge repair using MitraClip provided immediate hemodynamic stabilization in a 53-year-old woman with HOCM and severe MR, allowing weaning from mechanical ventilation.
Case Report (n=1)
MitraClip implantation followed by mavacamten may serve as a feasible rescue strategy and bridge to recovery in critically ill, inoperable patients with HOCM and refractory MR.
We report a rare case of MitraClip implantation as a bridge to survival in a patient with hypertrophic obstructive cardiomyopathy (HOCM) presenting with cardiogenic and septic shock.The 53-year-old woman had severe MR due to SAM and a LVOT gradient of 154 mmHg, which precluded urgent surgery.Transcatheter edge-to-edge repair (MTEER) using three MitraClips provided immediate hemodynamic stabilization-allowing successful weaning from vasopressors and mechanical ventilation.Following the intervention, Mavacamten therapy achieved sustained gradient reduction and further clinical improvement.This case highlights MTEER as a feasible rescue strategy in high-risk or inoperable HOCM patients with refractory MR, offering a bridge to recovery and definitive treatment. Short Summary (for figure legend or tweet/post caption)MitraClip implantation stabilized a critically ill HOCM patient with severe MR and LVOT obstruction when surgery was not feasible-demonstrating MTEER's role as a bridge to recovery.J o u r n a l P r e -p r o o f Suggested Hashtags #HOCM #MitraClip #MTEER #MitralRegurgitation #HeartFailure #StructuralHeart #InterventionalCardiology #Cardiology #CaseReport #Mavacamten #LVOTO #CriticalCare #BridgeToRecovery #HeartTeam #ShaareZedek #HebrewUniversity We describe a case of MitraClip implantation in a patient with hypertrophic obstructive cardiomyopathy (HOCM) as a bridge to survival.A 53-year-old woman with severe mitral regurgitation (MR) due to systolic anterior motion (SAM) and a left ventricular outflow tract gradient of 154 mmHg presented with pneumonia, respiratory failure, and hemodynamic collapse, precluding urgent surgery.Transcatheter edge-to-edge repair using three MitraClips significantly reduced MR, permitting liberation from mechanical ventilation and vasopressors.Subsequent Mavacamten therapy led to further stabilization.This case illustrates MitraClip as a feasible rescue strategy in high-risk HOCM patients with refractory MR.
Rabi et al. (Sat,) conducted a case report in Hypertrophic obstructive cardiomyopathy (HOCM) with severe mitral regurgitation and combined shock (n=1). Transcatheter edge-to-edge repair (MTEER) using MitraClip was evaluated on Hemodynamic stabilization and weaning from vasopressors and mechanical ventilation. Transcatheter edge-to-edge repair using MitraClip provided immediate hemodynamic stabilization in a 53-year-old woman with HOCM and severe MR, allowing weaning from mechanical ventilation.