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June 27, 2016EchocardiographyOpen Access

Left Ventricular Mechanics in Functional Ischemic Mitral Regurgitation in Acute Inferoposterior Myocardial Infarction

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Why the study?

Does ischemic mitral regurgitation affect left ventricular mechanics in patients with acute inferoposterior myocardial infarction?

Population

69 patients with first acute inferoposterior myocardial infarction treated with percutaneous coronary…

Comparison

Presence of ischemic mitral regurgitation vs No significant mitral regurgitation and healthy…

Design

Cohort

Key result

Ischemic mitral regurgitation in acute inferoposterior MI is associated with significantly worse radial and circumferential left ventricular deformation parameters compared to no significant MR.

Authors

ŽVŽivilė ValuckienėJOJustas OvsianasRARūta Ablonskytė-Dūdonienė

Discussion

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Overview

Speckle-tracking parameters should not yet guide acute ischemic MR management; leaves open their prognostic value in larger prospective cohorts.

Study Design

Type

Observational (n=104)

Structured PICO

Does ischemic mitral regurgitation affect left ventricular mechanics in patients with acute inferoposterior myocardial infarction?

P
Population
104 individuals, including 69 patients with a first acute inferoposterior MI and no structural valve abnormalities and 35 healthy matched controls, assessed within 48 hours of presentation.
E
Exposure
Presence of ischemic mitral regurgitation (grade ≥2)
C
Comparator
No significant mitral regurgitation (grade 0-I) and healthy controls
O
Outcome
Left ventricular mechanics (longitudinal, circumferential, and radial myocardial deformation parameters) assessed by 2D speckle-tracking echocardiographysurrogate

In patients with acute inferoposterior MI, the presence of ischemic mitral regurgitation is associated with impaired radial and circumferential left ventricular deformation, even when LVEF and longitudinal strain are similar.

Cite This Study

Valuckienė et al. (2016) conducted an observational in Acute inferoposterior myocardial infarction and ischemic mitral regurgitation (n=104). Ischemic mitral regurgitation (grade ≥2) vs. No significant MR (grade 0-I) and healthy subjects was evaluated on Left ventricular mechanics (ejection fraction, longitudinal, circumferential, and radial myocardial deformation parameters). Ischemic mitral regurgitation in acute inferoposterior MI is associated with significantly worse radial and circumferential left ventricular deformation parameters compared to no significant MR.

synapsesocial.com/papers/6a60198dc2662a747aa62f63https://doi.org/10.1111/echo.13240
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