⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

July 20, 2026Annals of the American Thoracic Society

Long-term efficacy and safety of rehabilitation in patients with pulmonary arterial hypertension: the FONCE-HTAP randomized controlled trial

Laurent Bertoletti Ségolène Turquier H Bouvaist Cécile Tromeur Irina Enache Marie‐France Seronde Claire Dauphin Rémi Diesler M Noirclerc Françis Couturaud Souad Bezzeghoud Carine Assante Céline Chapelle C Boissin David Montani Vincent Cottin Christophe Pison Frédéric Costes David Hupin For the FONCE-HTAP investigators

View at Publisher

Ask AI

Bookmark

Share

Key Points

The aim is to evaluate the long-term efficacy and safety of a supervised rehabilitation program on exercise tolerance in pulmonary arterial hypertension patients.
Randomized controlled trial with a Zelen design conducted across nine PAH centers in France.
Participants (N=47) received either usual follow-up or a supervised 3-month rehabilitation program.
Primary endpoint measured was endurance time during cardiopulmonary exercise testing at 12 months.
At 12 months, mean endurance time was significantly greater in the rehabilitation group (16.8 ± 20.0 min) compared to controls (8.0 ± 7.2 min, adjusted p = 0.047).
The risk of clinical worsening was lower in the rehabilitation group (RR 0.17, 95% CI 0.02-1.27; p = 0.055).
No deaths were reported during the study.

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Implication

Randomized trial assesses rehabilitation effects on exercise endurance in pulmonary arterial hypertension, suggesting improved outcomes.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Bertoletti et al. (2026) studied this question.

synapsesocial.com/papers/6a605d4a4163e025518d768a https://doi.org/10.1093/annalsats/aaoag193

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Effectiveness and safety of a simple home-based rehabilitation program in pulmonary arterial hypertension: an interventional pilot studyCohort Study · 2021 · 23 citations
2Impact of phase II cardiac rehabilitation on quality of life and functional capacity in patients with pulmonary arterial hypertensionother · 2026
3Short-term exercise training benefits pulmonary arterial hypertension patients2024 · 2 citations
4Beyond the clinic: a six-month home-based exercise and respiratory rehabilitation program improves functional capacity, respiratory muscle strength, and fatigue in chronic heart failureRCT · 2026
5The exercise in pulmonary arterial hypertension (ExPAH) study: A randomized controlled pilot of exercise training and multidisciplinary rehabilitation in pulmonary arterial hypertensionRCT · 2022 · 15 citations

More related papers

Reclaiming function: functional and prognostic gains through cardiac rehabilitation in pulmonary hypertension2026
The benefit of exercise‐based rehabilitation programs in patients with pulmonary hypertension: a systematic review and meta‐analysis of randomized controlled trials2021
Safety and effectiveness of standardized exercise training in patients with pulmonary hypertension associated with heart failure with preserved ejection fraction (TRAIN-HFpEF-PH): study protocol for a randomized controlled multicenter trial2023

More from Annals of the American Thoracic Society

A 41-year-old woman with Birt-Hogg-Dubé syndrome and persistent chest pain after air travelMon,
The septal pendulum: bidirectional interventricular septal excursion during initiation of left ventricular assist device supportMon,