Prevention of Experimental Rat Caries

Of practical aim to reach the simplest recording and severity of rats caries, 3133 lesions or cavities of carious affection appeared in 374 Wister rats of 7 different experimental caries researches on the high sugar diet, 6 PMV, were treated statistically (Table 1).Frequency of cavities differed at various locations of molars (Fig. 1), but almost coincide at right and left sides. Thus it is possible that one side of molars was submitted to the macerated preparate for easyer counting and another side was reserved for the histological examination. Negrecting smooth surface caries and cavities at irregular fissures, counting location were simplified into 12 fissures in one side and only 1.94% of cavities was discarded (Table 2). If two more regular fissures with fewer occurrance were neglected in scoring, cavities appeared on remaining 10 locations including 94.92% of total cavities (Table 2). These 12 fissures were location 1, and 2 at the 1st., location 5 and 6 at the 2nd., location 7 and 8 at the 3rd upper molars, and location 8 at 3rd., location 5 and 6 at the 2nd. and location 1, 2 and 3 at the 1st. lower molars, in order of caries frequency. When 10 locations were choised, two more fissures, location upper 7 and lower 8, could be subtracted from the 12 location system (refere with Fig. 1). Proposed models of the scoring table are shown in Fig. 3-A and 3-B. Grading of caries affection of one rat is possible to represent by number of cavities found on major 6 locations. According to the results at Table 3, the most probable pattern of conbineing locations would be as shown in Table 4.