Key result
Oestrogen may provide cardiovascular protection by suppressing sympathetic and elevating parasympathetic tone to the cardiovascular system.
Why the study?
Does oestrogen provide cardiovascular protection through modulation of autonomic nervous function?
Does oestrogen provide cardiovascular protection through modulation of autonomic nervous function?
Oestrogen may confer cardiovascular protection partly by shifting autonomic balance towards increased parasympathetic and decreased sympathetic tone.
Supports autonomic modulation as a mechanism of oestrogen's cardiovascular protection; leaves open clinical translation and prospective trials.
Experimental studies have provided evidence that the autonomic nervous activity is modulated by oestrogen. Such modulation at central and peripheral levels tends to suppress sympathetic but elevate parasympathetic tone to the cardiovascular system. Thus, available data support the view that cardiovascular protection by oestrogen may, at least in part, be mediated by its influence on autonomic nervous function.
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Du et al. (1995) reported a review. Oestrogen was evaluated. Oestrogen may provide cardiovascular protection by suppressing sympathetic and elevating parasympathetic tone to the cardiovascular system.
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