Facial rejuvenation is a hot topic in the field of plastic surgery. Autologous fat grafting has become an important method for facial rejuvenation due to its unique advantages, including good biocompatibility, minimal risk of immune rejection, and a natural appearance after transplantation. However, the uniform physical and biological characteristics of fat grafts limit their optimal effectiveness in different facial areas. Different mechanical processing methods of adipose tissue yield fat-derived products with unique biological components and physical characteristics, including high-density fat (HDF), adipose matrix complex (AMC), stromal vascular fraction gel (SVF-gel), and adipose collagen fragments (ACF). This article reports a case of a patient undergoing adipose component transplantation (ACT) and provides an in-depth discussion along with a review of relevant literature. It summarizes the current status of autologous adipose component transplantation in facial rejuvenation, explores the challenges and future directions of this novel facial fat grafting strategy, and aims to provide a reference for clinical practice and research.
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Xu et al. (2026) studied this question.
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