Key result
A CHA2DS2-VASc score ≥ 4 was associated with a significantly higher incidence of all-cause mortality (P<0.001), with an AUC of 0.79 (95% CI 0.69-0.88) for long-term mortality.
Why the study?
Does the CHA2DS2-VASc score predict all-cause mortality in patients with STEMI undergoing primary PCI?
Cohort (n=300)
Does the CHA2DS2-VASc score predict all-cause mortality in patients with STEMI undergoing primary PCI?
Effect estimate: AUC 0.79 (95% CI 0.69-0.88)
p-value: p=< 0.001
The CHA2DS2-VASc score is a strong predictor of in-hospital, 12-month, and long-term all-cause mortality in STEMI patients undergoing primary PCI.
May aid mortality risk stratification post-STEMI PCI; leaves open whether score-guided interventions improve outcomes.
BACKGROUND: Acute coronary syndrome is the most common cause of cardiac morbidity and death. Various scoring systems have been developed in order to identify patients who are at risk for adverse outcome and may benefit from more aggressive and effective therapies. OBJECTIVES: VASC score as a predictor of mortality inpatients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention (p-PCI). METHODS: VASC scores, patients were divided into three groups. Group 1: 0-1 points (n = 101), Group 2: 2-3 points (n = 129), and Group 3: 4-9 points (n = 70). The mean, median and minimum duration of follow-up were 21.7 ± 9.4, 21, and 12 months, respectively. All-cause mortality was defined as the primary endpoint of the study. RESULTS: VASC ≥ 4) had a significantly higher incidence of death [p (log-rank) < 0.001]. In ROC analysis, AUC values for in hospital, 12-month and long-term mortality were 0.88 (0.77-0.99 95% CI), 0.82 (0.73-0.92 95% CI) and 0.79 (0.69-0.88 95% CI), respectively. CONCLUSIONS: VASC score can be used for predicting both in-hospital, 12-month and long-term mortality in patients with STEMI who have undergone p-PCI.
No takes yet. Share an insight, caveat, or question.
Keskin et al. (2017) conducted a cohort in ST-segment elevation myocardial infarction (n=300). CHA2DS2-VASc score vs. Lower CHA2DS2-VASc score (0-3 points) was evaluated on All-cause mortality (AUC 0.79, 95% CI 0.69-0.88, p=< 0.001). A CHA2DS2-VASc score ≥ 4 was associated with a significantly higher incidence of all-cause mortality (P<0.001), with an AUC of 0.79 (95% CI 0.69-0.88) for long-term mortality.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: