Key result
An 8-week pilot of bidirectional electronic messaging and self-measured blood pressure significantly improved medication adherence (p=0.0001) and reduced systolic BP by 10.5 mm Hg (p=0.0027).
Why the study?
Non-Hispanic Black adults have high hypertension and cardiovascular disease burden, where medication nonadherence limits control and self-measured blood pressure improves diagnosis and adherence.
Does bidirectional electronic messaging and self-measured blood pressure improve medication adherence and blood pressure in adults with uncontrolled hypertension?
Does bidirectional electronic messaging and self-measured blood pressure improve medication adherence and blood pressure in adults with uncontrolled hypertension?
Effect estimate: Adherence median change -0.5; SBP mean decrease 10.5 mm Hg
p-value: p=0.0001 (adherence), 0.0027 (SBP)
Bidirectional electronic messaging combined with self-measured blood pressure significantly improved medication adherence and systolic blood pressure in a predominantly Non-Hispanic Black cohort with uncontrolled hypertension.
May support BEM in community HTN care for NHB adults; leaves open efficacy in larger trials.
Study objective: Non-Hispanic Black (NHB) adults have high hypertension (HTN) and cardiovascular disease (CVD) burden. Medication nonadherence limits control and self-measured blood pressure (SMBP) improves diagnosis and adherence. This predominantly NHB cohort pilot, via community-clinical linkages, with uncontrolled HTN and low adherence, utilized bidirectional electronic messaging (BEM) with team-care, to assess medication adherence, quality of life, and BP. Setting: Academic clinic and community sources. Design: Recruitment included: uncontrolled HTN (BP ≥130/80 mm Hg), low adherence (Krousel-Wood Medication Adherence Scale (K-Wood-MAS-4) ≥1 score), and smartphone access. Participants and interventions: Participants (N = 36) received validated Bluetooth-enabled BP devices, synced to smartphones, via a secured cloud-based application. Main outcome measures: Demographics, adherence scores, Centers for Disease Control and Prevention (CDC) health-related quality of life (HRQOL-14), BP, body mass index (BMI), 8 weeks daily BEM, SMBP and text responses were obtained. Results: Age was 58.7 ± 12.8 years; BMI 34.8 ± 7.9; 63.9 % female; 88.9 % self-identified NHB adults; 72.2 % with obesity; 74.3 % with diabetes. K-Wood-MAS-4 adherence composite score improved: 2.19 to 1.58 (median -0.5, p = 0.0001). Systolic BP decreased by 10.5 ± 20.0 mm Hg (median -11.0, p = 0.0027). QOL did not significantly change. Mean 7-day average SBP/DBP differences were -4.94 ± 16.82 (median -3.5, p = 0.0285) and -0.17 ± 7.42 (median 0, p = 0.7001), respectively. Social support with taking BP medication was: "yes" (n = 19); 143.8 mm Hg to 131.5 mm Hg (median -12.5, p = 0.0198) and "no" (n = 14); 142.32 mm Hg to 130.25 mm Hg (median -4.0, p = 0.0771). Conclusions: Community-clinical linkages and SMBP with BEM significantly improved medication adherence and SBP without modifying pharmacotherapy.
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Ferdinand et al. (2023) studied Uncontrolled hypertension and low medication adherence (n=36). Bidirectional electronic messaging (BEM) with team-care and self-measured blood pressure (SMBP) was evaluated on Medication adherence (K-Wood-MAS-4 composite score) and systolic blood pressure (Adherence median change -0.5; SBP mean decrease 10.5 mm Hg, p=0.0001 (adherence), 0.0027 (SBP)). An 8-week pilot of bidirectional electronic messaging and self-measured blood pressure significantly improved medication adherence (p=0.0001) and reduced systolic BP by 10.5 mm Hg (p=0.0027).
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