Key result
Transcatheter bicaval valve implantation with the TricValve improved symptoms, reducing NT-proBNP from 5,648 to 2,072 pg/ml and increasing 6-minute walk distance from 320 to 420 meters at 3 months.
Why the study?
Transcatheter tricuspid valve intervention is usually performed on compassionate grounds, prompting exploration of its elective use in severe atrial functional tricuspid regurgitation.
Case Report (n=1)
No
Answers are grounded in this paper and cite their sources.
May support elective TricValve use in atrial functional TR; leaves open safety and efficacy in larger prospective studies.
Background: Transcatheter tricuspid valve intervention has recently emerged as a viable alternative to surgery for patients with symptomatic severe tricuspid regurgitation (TR). Though usually performed on the basis of compassionate grounds, we are now exploring the extension of its usage as an elective option in a patient with severe atrial functional tricuspid regurgitation. Aims: The aim of this study was to select a suitable patient and proceed with the implantation of the TricValve in order to provide symptomatic relief as well as to improve morbidity and mortality. Methods: A 67-year-old woman had underlying atrial fibrillation and severe tricuspid regurgitation. Despite optimised medical therapy, she remained symptomatic with elevated NT-proBNP levels. As the patient refused surgery on multiple occasions, we chose a percutaneous procedure guided by transoesophageal echocardiography and fluoroscopy. Results: The procedure was uneventful and the patient was discharged. At 3-month follow-up, there was marked improvement clinically and biochemically. Conclusions: Bicaval valve implantation with the TricValve is a viable alternative to surgery in patients with symptomatic severe tricuspid regurgitation. This intervention is crucial as we are now able to intervene before irreversible right ventricular dysfunction sets in.
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Jin et al. (2022) conducted a case report in Severe atrial functional tricuspid regurgitation (n=1). Transcatheter bicaval valve implantation (TricValve) was evaluated on Clinical and biochemical improvement (NYHA class, NT-proBNP, 6MWT). Transcatheter bicaval valve implantation with the TricValve improved symptoms, reducing NT-proBNP from 5,648 to 2,072 pg/ml and increasing 6-minute walk distance from 320 to 420 meters at 3 months.
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