Key result
Symptomatic neurological complications before surgery in patients with left-sided infective endocarditis were associated with a significantly increased risk of in-hospital mortality (14.3% vs 4.4%; OR 10.25).
Why the study?
The study aimed to investigate the surgical treatment of left-sided infective endocarditis in patients with symptomatic neurological complications before surgery.
Does the presence of symptomatic neurological complications before surgery increase in-hospital mortality and intubation time in patients undergoing cardiac surgery for left-sided infective endocarditis?
Cohort (n=832)
No
Does the presence of symptomatic neurological complications before surgery increase in-hospital mortality and intubation time in patients undergoing cardiac surgery for left-sided infective endocarditis?
Preoperative symptomatic neurological complications in patients with left-sided infective endocarditis are associated with higher in-hospital mortality and prolonged intubation after cardiac surgery.
May warrant perioperative caution in left-sided IE with neurological complications; leaves open optimal surgical timing.
Introduction We aimed to investigate surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery. Methods This was a retrospective study of patients with left-sided infective endocarditis and symptomatic neurological complications before surgery undergoing cardiac surgery between January 2006 and November 2022 at our hospital. Results Eight hundred thirty-two patients were divided into group with symptomatic neurological complications before surgery ( n = 112) and without symptomatic neurological complications before surgery ( n = 720). There were 48 operative deaths (5.4%). Univariate and multivariate analyses showed that symptomatic neurological complications before surgery is statistically significantly associated with in-hospital mortality following cardiac surgery and prolonged intubation time. Conclusions Our study showed that symptomatic neurological complications before surgery are associated with increased in-hospital mortality following cardiac surgery and prolonged intubation time.
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Huang et al. (2023) conducted a cohort in Left-sided infective endocarditis (n=832). Symptomatic neurological complications before surgery vs. No symptomatic neurological complications before surgery was evaluated on In-hospital mortality (OR 10.249, 95% CI 4.698-22.356, p=<0.001). Symptomatic neurological complications before surgery in patients with left-sided infective endocarditis were associated with a significantly increased risk of in-hospital mortality (14.3% vs 4.4%; OR 10.25).
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