Key result
ANCA-associated vasculitis linked to ~90% higher risk of MI vs. the general population.
Why the study?
Does ANCA-associated vasculitis increase the risk of myocardial infarction compared to the background population?
Population
325 patients diagnosed with ANCA-associated vasculitis between 1997-2016 in Skåne, Sweden, and age- and…
Comparison
ANCA-associated vasculitis diagnosis vs Age- and sex-matched reference subjects from the…
Design
Cohort
Authors
Loading...
Patients with ANCA-associated vasculitis have a nearly twofold increased risk of myocardial infarction compared to the general population, particularly in the first 3 months following diagnosis.
Cohort (n=3,045)
Does ANCA-associated vasculitis increase the risk of myocardial infarction compared to the background population?
Relative Risk: 1.9 (95% CI 1.3–2.8)
Patients with ANCA-associated vasculitis have a nearly twofold increased risk of myocardial infarction compared to the general population, particularly in the first 3 months following diagnosis.
Borgas et al. (2025) conducted a cohort in ANCA-associated vasculitis (AAV) (n=3,045). ANCA-associated vasculitis vs. Background population was evaluated on Incidence of first myocardial infarction (IRR 1.9, 95% CI 1.3 to 2.8). ANCA-associated vasculitis was associated with a higher incidence of myocardial infarction compared to the background population (IRR 1.9; 95% CI 1.3-2.8).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: