Key result
Cardiovascular magnetic resonance evaluation of 203 healthy volunteers demonstrated that left atrial size decreases with older age and normalization to body size overcomes sex-dependency.
Why the study?
What are the normal reference values for left atrial size and function using a fast CMR approach in healthy volunteers?
Cross-Sectional (n=203)
What are the normal reference values for left atrial size and function using a fast CMR approach in healthy volunteers?
Answers are grounded in this paper and cite their sources.
This study provides normal reference values for left atrial size and function using a fast CMR approach, highlighting that LA size decreases with age and should be indexed to body surface area to overcome sex differences.
OBJECTIVES: In recent years the impact of the left atrium (LA) has become more evident in different cardiovascular pathologies. We aim to provide LA parameters in healthy volunteers for cardiovascular magnetic resonance (CMR) using a fast approach. DESIGN: We analyzed 203 healthy volunteers (mean age 44.6 years (y), range 19y-76y) at 1.5 and 3.0 Tesla (T) using steady-state free precession (SSFP) cine in routine long axis view. Left atrial enddiastolic volume (LA-EDV), endsystolic volume (LA-ESV), stroke volume (LA-SV) and ejection fraction (LA-EF) were quantified and indexed to body-surface-area (BSA). Dependency on age and sex was analyzed. RESULTS: (p = .71)). LA-EDV/BSA decreased with older age. CONCLUSIONS: Reference values for LA size and function based on a fast approach are provided. LA size decreases with older age. Normalization to body size overcomes sex-dependency. Reports should be related to body size.
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Funk et al. (2018) conducted a cross-sectional in Healthy (n=203). Cardiovascular magnetic resonance (CMR) was evaluated on Left atrial parameters (LA-EDV, LA-ESV, LA-SV, LA-EF) indexed to body-surface-area. Cardiovascular magnetic resonance evaluation of 203 healthy volunteers demonstrated that left atrial size decreases with older age and normalization to body size overcomes sex-dependency.
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