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Four billion years of microbial history, 200,000 years of human history, which is 200,000 years of history with microbes, and 130 years of microbiology history. Such is the broad sweep of Deadly Companions—How Microbes Shaped Our History by Dorothy H. Crawford. The dust jacket of the book has on it the striking image of a plague doctor, gowned and wearing a beaked mask.
Brian J. Wilkinson (Sat,) studied this question.