Key result
A deep learning algorithm automatically classified stroke size on diffusion-weighted imaging in patients with atrial fibrillation, achieving 87.4% agreement and a Cohen's kappa of 0.81 compared to expert consensus.
Why the study?
Does a deep learning algorithm accurately and automatically classify stroke size on DWI scans in patients with atrial fibrillation-related ischemic stroke compared to expert consensus?
Does a deep learning algorithm accurately and automatically classify stroke size on DWI scans in patients with atrial fibrillation-related ischemic stroke compared to expert consensus?
Effect estimate: Cohen's kappa 0.81 (95% CI 0.78-0.84)
A deep learning algorithm demonstrated excellent accuracy in automatically classifying stroke size on DWI, which may assist in optimizing DOAC initiation timing in patients with AF-related ischemic stroke.
May aid rapid AF stroke sizing on DWI; leaves open prospective validation and outcome impact.
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Kim et al. (2025) conducted a letter in Acute ischemic stroke with atrial fibrillation (n=2,356). Deep learning algorithm (EfficientNet3D) for stroke size classification vs. Expert consensus (vascular neurologists) was evaluated on Agreement in stroke size classification (minor, moderate, major) between the deep learning algorithm and expert consensus in the external validation dataset (Cohen's kappa 0.81, 95% CI 0.78-0.84). A deep learning algorithm automatically classified stroke size on diffusion-weighted imaging in patients with atrial fibrillation, achieving 87.4% agreement and a Cohen's kappa of 0.81 compared to expert consensus.
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