Sizzling in Paris: Are aptamers the hottest modality in the expanding RNA universe?

Vittorio DeFranciscis; Paloma H. Giangrande

doi:10.1016/j.omtn.2026.103007

July 21, 2026Molecular Therapy — Nucleic AcidsOpen Access

Sizzling in Paris: Are aptamers the hottest modality in the expanding RNA universe?

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Key Points

This work explores the role of aptamers within the expanding field of RNA technologies. The focus is on their potential and innovations in medical applications.
Participants discussed breakthroughs in extrahepatic delivery systems for RNA-based therapies.
Sessions included presentations on chemical modifications enhancing aptamer stability and function.
The conference showcased next-generation aptamer technologies that improve targeting efficiency.
Significant advancements were presented in aptamer-based delivery systems for therapeutic applications.
New chemical modifications were reported to enhance the efficacy of RNA molecules.
Next-generation technologies are expected to significantly improve aptamer performance in clinical settings.

Implication

Conference discusses advancements in aptamers, delivery methods, and chemical modifications in RNA technology.

Abstract

This week, the international RNA community converged at the historic Institut Pasteur in Paris, France, for the 17th RNA Consortium Meeting. While the summer temperatures across Paris were undeniably scorching (and AC a premium), the scientific discourse inside the auditorium was equally hot, driven by groundbreaking advancements in extrahepatic delivery, chemical modifications, and next-generation aptamer technologies.

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Cite This Study

DeFranciscis et al. (2026) studied this question.

synapsesocial.com/papers/6a61ae6bfaa9903c51169c33 https://doi.org/10.1016/j.omtn.2026.103007

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Sizzling in Paris: Are aptamers the hottest modality in the expanding RNA universe?

Key Points

Implication

Abstract

Discussion

Cite This Study

Sizzling in Paris: Are aptamers the hottest modality in the expanding RNA universe?

Key Points

Implication

Abstract

Discussion

Cite This Study

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