Acute Encephalopathy in an Infant

ONSET VITAMIN K DEFICIENCY BLEEDING Late-onset vitamin K deficiency bleeding can occur from 1 week to as late as 6 months of age and carries up to 20% mortality. 1Elevated INR reflects a functional deficiency of vitamin K-dependent clotting factors.The patient exhibited Cushing triad (bradycardia, hypertension, respiratory irregularity), indicating increased intracranial pressure (ICP) from hemorrhage and obstructive hydrocephalus. 2 Intermittent esotropia suggests sixth cranial nerve palsy, commonFIGURE 1. Sagittal noncontrast head CT demonstrating acute intraparenchymal hemorrhage in the left basal ganglia with associated edema.CT, computed tomography.