One-step synthesis of multiple organic compounds in room temperature settings, suggesting efficient chemical processes.
A one-step method for the synthesis of α,β-unsaturated imines, hydrazones, semicarbazones, and thiosemicarbazones has been developed based on the reaction of 3-arylidene-1-pyrrolines with 2,3-diaminomaleonitrile, 4-methylpiperazin-1-amine, semicarbazide, and thiosemicarbazide in benzene or ethanol at room temperature. The structures of the obtained compounds were established by 1H and 13C NMR spectroscopy and elemental analysis.
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Sidlyaruk et al. (2026) studied this question.
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