Key result
Fibreoptic orotracheal and nasotracheal intubations caused similar circulatory responses in anesthetized adult females, but the tachycardic response to orotracheal intubation lasted longer.
Why the study?
Does fibreoptic orotracheal intubation compared to nasotracheal intubation cause different circulatory responses in adult female patients under general anaesthesia?
RCT (n=60)
Randomly assigned
Does fibreoptic orotracheal intubation compared to nasotracheal intubation cause different circulatory responses in adult female patients under general anaesthesia?
Fibreoptic orotracheal and nasotracheal intubations cause similar magnitudes of circulatory responses in anesthetized adult females, though tachycardia lasts longer with the oral route.
Oral and nasal fibreoptic intubation under GA elicit comparable pressor responses; leaves open whether route affects outcomes in higher-risk patients.
The circulatory responses to fibreoptic intubation under general anaesthesia were studied in 60 adult female patients who were randomly assigned to receive either the oral or nasal route for insertion. Non-invasive blood pressure and heart rate were recorded before anaesthesia induction (baseline values), immediately after anaesthesia induction (post-induction values), at intubation and every minute for a further 5 min. The product of heart rate and systolic blood pressure (rate pressure product) at every time point was also calculated. The results showed that both fibreoptic orotracheal intubation and fibreoptic nasotracheal intubation resulted in significant increases in blood pressure, heart rate and rate pressure product compared to baseline and post-induction values. The times required to reach the maximum values of systolic blood pressure and heart rate were significantly longer in the fibreoptic nasotracheal intubation group than in the fibreoptic orotracheal intubation group. There were no significant differences between the two groups in blood pressure, heart rate and rate pressure product at any measuring point, or in the maximum values during observation. The time required for recovery of systolic blood pressure to the post-induction value was not significantly different between the two groups, but the time required for recovery of heart rate to post-induction value was significantly longer in the fibreoptic orotracheal intubation group than in the fibreoptic nasotracheal intubation group. It was concluded that both fibreoptic orotracheal and fibreoptic nasotracheal intubations could cause a similar magnitude of circulatory responses in general anaesthetised, female adults, but the tachycardic response to fibreoptic orotracheal intubation lasted longer than that to fibreoptic nasotracheal intubation.
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Xue et al. (2006) conducted an RCT in General anaesthesia requiring fibreoptic intubation (n=60). Fibreoptic orotracheal intubation vs. Fibreoptic nasotracheal intubation was evaluated on Circulatory responses (blood pressure, heart rate, rate pressure product). Fibreoptic orotracheal and nasotracheal intubations caused similar circulatory responses in anesthetized adult females, but the tachycardic response to orotracheal intubation lasted longer.
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