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July 23, 2026Cancer Biology and MedicineOpen Access

Harnessing the microbiome: a new frontier in lung cancer immunotherapy

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Authors

KFKexin FengJWJun WangSWShuai Wang

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Overview

This comprehensive review discusses microbiome influence on lung cancer immunotherapy and predictive biomarkers, indicating novel approaches for personalized treatments.

Key Points

  • To explore the role of the microbiome as a predictor of immunotherapy outcomes in lung cancer.
  • Reviewed existing literature on microbiome profiles in lung cancer.
  • Investigated mechanisms of microbiome-tumor interactions.
  • Evaluated strategies for microbiome-targeted interventions.
  • Identified distinct microbiome profiles correlating with immunotherapy effectiveness.
  • Highlighted potential of microbial metabolites as predictive biomarkers.
  • Proposed future strategies for integrating microbiome insights in personalized treatment approaches.

Cite This Study

Feng et al. (2026) studied this question.

synapsesocial.com/papers/6a61afaefaa9903c5116a6b7https://doi.org/10.20892/j.issn.2095-3941.2025.0177
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