Answers are grounded in this paper and cite their sources.
This review analyzes how exercise impacts neuroplasticity and neurotransmission in Parkinson's patients, suggesting therapeutic potentials.
Epidemiological and clinical trials have suggested that exercise is beneficial for patients with Parkinson's disease (PD). However, the underlying mechanisms and potential for disease modification are currently unknown. This review presents current findings from our laboratories in patients with PD and animal models. The data indicate that alterations in both dopaminergic and glutamatergic neurotransmission, induced by activity-dependent (exercise) processes, may mitigate the cortically driven hyper-excitability in the basal ganglia normally observed in the parkinsonian state. These insights have potential to identify novel therapeutic treatments capable of reversing or delaying disease progression in PD.
No takes yet. Share an insight, caveat, or question.
Petzinger et al. (2010) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: