Why the study?
What are the afferent mechanisms of the initial heart rate response to standing in healthy subjects?
Population
43 healthy subjects
Comparison
Postural change maneuvers including free… vs Comparison between different maneuvers
Design
Other
Follow-up
Immediate (up to ~20 seconds)
Key result
Active standing evokes an immediate, large, bimodal increase of heart rate of about 20 seconds duration that far exceeds the gradual heart rate rise induced by 70 degrees head-up tilt.
Authors
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Active and passive posture changes differ in early CV effects; extends reflex research but leaves mechanisms and clinical relevance open.
What are the afferent mechanisms of the initial heart rate response to standing in healthy subjects?
Active and passive changes of posture result in fundamentally different cardiovascular effects for about 20 seconds, involving multiple reflex mechanisms.
Borst et al. (1982) studied Healthy (n=43). Active standing vs. 70 degrees head-up tilt, handgrip, and contraction of abdominal and leg muscles was evaluated on Initial heart rate response. Active standing evokes an immediate, large, bimodal increase of heart rate of about 20 seconds duration that far exceeds the gradual heart rate rise induced by 70 degrees head-up tilt.