Perspectives on nanomaterial-empowered bioremediation of heavy metals by photosynthetic microorganisms

Environmental remediation of heavy metals (HMs) is a crucial aspect of sustainable development, safeguarding natural resources, biodiversity, and the delicate balance of ecosystems, all of which are critical for sustaining life on our planet. The bioremediation of HMs by unicellular phototrophs harnesses their intrinsic detoxification mechanisms, including biosorption, bioaccumulation, and biotransformation. These processes can be remarkably effective in mitigating HMs, particularly at lower contaminant concentrations, surpassing the efficacy of conventional physicochemical methods and offering greater sustainability and cost-effectiveness. Here, we explore the potential of various engineered nanomaterials to further enhance the capacity and efficiency of HM bioremediation based on photosynthetic microorganisms. The critical assessment of the interactions between nanomaterials and unicellular phototrophs emphasised the ability of tailored nanomaterials to sustain photosynthetic metabolism and the defence system of microorganisms, thereby enhancing their growth, biomass accumulation, and overall bioremediation capacity. Key factors that could shape future research efforts toward sustainable nanobioremediation of HM are discussed, and knowledge gaps in the field have been identified. This study sheds light on the potential of nanobioremediation by unicellular phototrophs as an efficient, scalable, and cost-effective solution for HM removal. • Nanomaterials have untapped potential to improve heavy metal mitigation by unicellular phototrophs. • Redox and surface properties of nanomaterials can increase reduction and biosorption of heavy metals by unicellular phototrophs. • Nanomaterial-mediated hormetic effects in unicellular phototrophs can support heavy metal mitigation process. • Nanomaterials can enhance heavy metal bioremediation by altering the bioavailability of the contaminants. • Nanobioremediation by unicellular phototrophs is proposed as efficient, scalable and cost-effective solution for heavy metal removal.