Key result
Closed-chest ablation using direct-current shocks successfully controlled pacemaker-mediated arrhythmias in 3 patients over a 6 to 8 month follow-up.
Why the study?
Does closed-chest direct-current ablation control pacemaker-mediated tachycardias in patients with drug-resistant arrhythmias?
Case Report (n=3)
Does closed-chest direct-current ablation control pacemaker-mediated tachycardias in patients with drug-resistant arrhythmias?
Closed-chest direct-current ablation of the AV node or accessory pathways is an effective treatment modality for drug-resistant pacemaker-mediated tachycardias.
Three patients with pacemaker interactive drug resistant tachycardia underwent invasive electrophysiological studies. In the first patient, the retrograde conduction of the artificial reciprocating tachycardia was provided by two right-sided accessory pathways and the antegrade conduction by an atrial synchronous pulse generator. In addition, AV-nodal tachycardia occurred alternately. In the second patient with intermittent atrial flutter, the AV node and, coincidentally, an AV sequential pulse generator provided high-rate antegrade conduction to the ventricles. In the third patient with surgical complete heart block, intermittent AV-nodal tachycardia induced retrograde atrial activation while an atrial synchronous pacemaker provided the antegrade conduction. Electrode catheter exploration of the heart allowed localization and closed-chest ablation of the accessory pathways or AV node by delivering two to seven 200-joule direct-current shocks through the appropriate electrode of the exploring catheter. Thereby, pacemaker-mediated arrhythmias could be controlled in these patients in the follow-up of 6 to 8 months.
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Wéber et al. (1984) conducted a case report in Pacemaker interactive drug resistant tachycardia (n=3). Closed-chest ablation of accessory pathways or AV node was evaluated on Control of pacemaker-mediated arrhythmias. Closed-chest ablation using direct-current shocks successfully controlled pacemaker-mediated arrhythmias in 3 patients over a 6 to 8 month follow-up.
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