Cryptosporidium Infection and CD4 Counts

Brief Reports15 May 1992Cryptosporidium Infection and CD4 CountsTimothy Flanigan, MD, Christopher Whalen, MD, John Turner, MD, Rosemary Soave, MD, Joseph Toerner, MD, Diane Havlir, MD, Donald Kotler, MDTimothy Flanigan, MD, Christopher Whalen, MD, John Turner, MD, Rosemary Soave, MD, Joseph Toerner, MD, Diane Havlir, MD, Donald Kotler, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-116-10-840 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCryptosporidiumis a coccidian parasite that infects the gastrointestinal tract in humans and can cause severe enteritis and malabsorption. Cryptosporidiosis is selflimited in immunocompetent persons, whereas in persons with the acquired immunodeficiency syndrome (AIDS),Cryptospondiuminfection causes persistent enteritis that is usually lifelong and refractory to treatment (1). In our clinical practices, we observed men infected with the human immunodeficiency virus (HIV) who had self-limited diarrhea due toCryptosporidiuminfection. To better define the laboratory and clinical characteristics associated with self-limited compared with persistent disease, we did a retrospective chart review of HIV-seropositive patients withCryptosporidiuminfection. We hypothesized that...References1. FayerUngar RL. Cryptosporidium spp. and cryptosporidiosis. Microbiol Rev. 1986;50:458-83. CrossrefMedlineGoogle Scholar2. . Revision of the CDC surveillance case definition for acquired immunodeficiency syndrome. MMWR. 1987;36(Suppl 1S):3S-15S. Google Scholar3. SUGI Supplemental Library User's Guide, Version 5. Cary, North Carolina: SAS Institute Inc.; 1986:270-94. Google Scholar4. SoaveJohnson RW. Cryptosporidium and Isospora belli infections. J Infect Dis. 1988;157:225-9. CrossrefMedlineGoogle Scholar5. GreenbergMirBankSiegal RRSF. Resolution of intestinal cryptosporidiosis after treatment of AIDS with AZT. Gastroenterology. 1989;97:1327-30. CrossrefMedlineGoogle Scholar6. ConnollyDrydenShansonGazzard GMDB. Cryptosporidial diarrhoea in AIDS and its treatment. Gut. 1988;29:593-7. CrossrefMedlineGoogle Scholar7. JacobsonHopewellYajkoHadleyLazarusMohanty MPDWEP. Natural history of disseminated Mycobacterium avium complex infection in AIDS. J Infect Dis. 1991;164:994-8. CrossrefMedlineGoogle Scholar8. HojlyngHenriksenGaubHjeltMathiesonJepson NSJKLS. Cryptosporidium diarrhea in AIDS patients treated with hyperimmune bovine colostrum. VI International Conference on AIDS. 20-24 June 1990. San Francisco, California. 1990;TH.B.521:253. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: For current author affiliations and addresses, see end of text. 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