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Patients affected by diabetes show anincreased risk of cardiovascular dis-ease (CVD) and mortality that re-duces their life expectancy by 5–15 years (depending on the age at diagnosis). An 18-year follow-up study from Finland demonstrated a similar impact of type 1 and type 2 diabetes on cardiovascular mortality, with an increased risk of 5.2 and4.9 times for type 1 and type 2 diabetes, respectively (1). In type 1 diabetes, follow-up results from a large randomized clini-cal trial suggest that the improvement of metabolic control, obtained through in-tensive insulin treatment, can prevent CVD in the long term. On the other hand, despite some encouraging results
Mannucci et al. (Wed,) studied this question.