Key result
Patients with repaired coarctation of the aorta had significantly increased peak systolic blood pressure during exercise compared to healthy reference values (Z-score 1.063 ± 1.347).
Why the study?
What are the current reference values for peak exercise systolic blood pressure in children, and how do patients with repaired coarctation of the aorta compare?
Cross-Sectional (n=209)
What are the current reference values for peak exercise systolic blood pressure in children, and how do patients with repaired coarctation of the aorta compare?
This study establishes updated reference values for peak exercise systolic blood pressure in children and demonstrates that patients with repaired coarctation of the aorta have significantly higher peak SBP than healthy peers.
Answers are grounded in this paper and cite their sources.
Updated pediatric peak SBP references may refine exercise test interpretation; extends prior norms but leaves validation and adoption open.
BACKGROUND: Hemodynamic responses to exercise are used as markers of diagnosis for cardiac diseases, systolic blood pressure (SBP) especially. However, the reference values for SBP in children at peak exertion level are outdated. This study aimed to establish current reference values for SBP, rate pressure product (RPP), and circulatory power (CircP). METHODS: Data from children who previously underwent cardiopulmonary exercise testing were categorized as healthy (N = 184; age 12.6 ± 2.9 years), and CoA patients (N = 25; age 13.0 ± 3.2 years). With the Lambda-Mu-Sigma (LMS) method, percentile curves were made for SBP, CircP, and RPP in function of peak work rate (Wpeak). Data of CoA patients were used to validate the reference values. RESULTS: Wpeak was the best predictor of peak SBP during exercise. The prediction equations for SBP, CircP and RPP were: (0.2853 x Wpeak) + 111.46; (10.56 x Wpeak) + 2550.2 and (61.879 x Wpeak) + 19.887, respectively. CoA patients showed significantly increased values for peak SBP (Z-score 1.063 ± 1.347). CONCLUSION: This study provides reference values for SBP, RPP, and CircP at peak exercise. These values can be used for objective evaluation of participants 6-18 years of age in a Dutch population.
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Kaafarani et al. (2017) conducted a cross-sectional in Repaired coarctation of the aorta (n=209). Repaired coarctation of the aorta vs. Healthy children was evaluated on Peak systolic blood pressure (SBP) during exercise (Z-score 1.063). Patients with repaired coarctation of the aorta had significantly increased peak systolic blood pressure during exercise compared to healthy reference values (Z-score 1.063 ± 1.347).
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