Key result
Children with congenital heart disease had lower peak oxygen uptake than healthy controls (35.5 vs 42.4 ml/min/kg; P<0.001), but no difference in oxygen uptake at the ventilatory threshold.
Why the study?
Does congenital heart disease reduce submaximal and peak exercise performance in children compared to healthy controls?
Case-Control (n=176)
No
Does congenital heart disease reduce submaximal and peak exercise performance in children compared to healthy controls?
Answers are grounded in this paper and cite their sources.
Supports encouraging activity without restriction in children with CHD; extends adult findings to modern pediatric cohorts but leaves practice change open pending prospective data.
OBJECTIVES: In several former studies, adolescents and adults with congenital heart disease (CHD) had a reduced exercise capacity even with defects considered to be simple. Currently, children might get better medical management and less restrictions concerning an active lifestyle or sports activities. The exercise performance of this new generation of children with CHD has to be evaluated. METHODS: In the year 2010, 88 children (12.7 years, 52 males), 11-14 years old, with various CHD performed a cardiopulmonary exercise test in our institution. These children were matched for age and gender with healthy subjects who underwent the same procedure at a school survey. RESULTS: In comparison with healthy controls, children with CHD had a diminished peak oxygen uptake (CHD: 35.5 ml/min/kg vs controls: 42.4 ml/min/kg; P < 0.001) corresponding to 87.1% (CHD) and 99.5% (Controls) of the reference value, respectively. Peak oxygen uptake decreased with the severity of the heart defect (r = -0.410; P < 0.001). However, there was no difference in oxygen uptake at the ventilatory threshold (CHD: 20.6 ml/min/kg vs controls: 21.5 ml/min/kg; P = 0.68). CONCLUSIONS: Currently, children with CHD are not limited in their submaximal exercise performance. However, there is still a reduction in peak oxygen uptake.
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Müller et al. (2013) conducted a case-control in congenital heart disease (n=176). Congenital heart disease vs. Healthy subjects was evaluated on peak oxygen uptake (p=< 0.001). Children with congenital heart disease had lower peak oxygen uptake than healthy controls (35.5 vs 42.4 ml/min/kg; P<0.001), but no difference in oxygen uptake at the ventilatory threshold.
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