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September 20, 2011The Journal of PhysiologyOpen Access

Prior endurance exercise prevents postprandial lipaemia‐induced increases in reactive oxygen species in circulating CD31+ cells

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Key result

Prior endurance exercise (~50 min) completely prevented postprandial lipaemia-induced increases in reactive oxygen species in CD31(+) cells in 10 healthy men.

Why the study?

Does prior endurance exercise prevent postprandial lipaemia-induced increases in reactive oxygen species in circulating angiogenic cells in healthy men?

Population

10 healthy men

Comparison

~50 min of prior endurance exercise before… vs Ingesting a high fat meal without prior…

Design

Other

Follow-up

4 hours

Authors

NJNathan T. JenkinsUniversity of GeorgiaRLRian Q. LandersHeart Rhythm SocietySTSunny R. ThakkarTemple College

Discussion

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Implication

May blunt postprandial cellular oxidative stress; hypothesis-generating before clinical translation.

Structured PICO

Does prior endurance exercise prevent postprandial lipaemia-induced increases in reactive oxygen species in circulating angiogenic cells in healthy men?

P
Population
10 healthy men evaluated before and 4 hours after ingesting a high-fat meal with or without prior endurance exercise.
I
Intervention
~50 min of prior endurance exercise before ingesting a high fat meal
C
Comparator
Ingesting a high fat meal without prior endurance exercise (control trial)
O
Outcome
Intracellular reactive oxygen species (ROS) production in circulating angiogenic cell (CAC) subpopulations (CD34+, CD31+/CD14-/CD34-, and CD31+/CD14+/CD34-) before and 4 h after mealsurrogate

Prior endurance exercise mitigates cellular oxidative stress and systemic cardiovascular risk markers induced by a high-fat meal in healthy men.

Cite This Study

Jenkins et al. (2011) studied Healthy (n=10). Prior endurance exercise vs. No prior exercise (control trial) was evaluated on Intracellular reactive oxygen species (ROS) production in circulating angiogenic cell subpopulations. Prior endurance exercise (~50 min) completely prevented postprandial lipaemia-induced increases in reactive oxygen species in CD31(+) cells in 10 healthy men.

synapsesocial.com/papers/6a6261e36e9a4038e37dae2ehttps://doi.org/10.1113/jphysiol.2011.215277
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