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Benzothiazoles play significant roles in modern therapeutical chemistry owing to their significant effects and their integration into various pharmaceutical agents for treating critical diseases. Several approved, investigational, and experimental benzothiazole-based drugs have been accomplished. Novel strategies targeting therapeutical benzothiazoles and up-to-date synthetic strategies of anti-neurodegenerative, anti-inflammatory, antitumor, anti-microbial, and anti-viral benzothiazoles are well-recognized and reviewed. The biological investigations of the newly synthesized compounds are emphasized. This comprehensive review is considered as a valuable source in drug discovery and development.
Mohamed‐Ezzat et al. (Wed,) studied this question.