On the contrary! A rhodium-catalyzed restructuring reaction of 3-arylcyclobutanols to 1-indanols is reported, in which two chiral quaternary carbon centers are formed in a highly enantioselective fashion by a sequence of two contradictory elementary steps, that is, carbon–carbon bond cleavage and carbon–carbon bond formation.
No takes yet. Share an insight, caveat, or question.
Shigeno et al. (2009) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: