Many organisms use a most unexpected strategy for forming large single crystals such as those that make up mineralized skeletal parts. Although nucleation and growth of a crystal occur from a solid disordered phase that has the characteristics of a melt phase, the process is accomplished at ambient temperatures and pressures. This strategy allows organisms to mold the crystals into unusual shapes and orient them at will.
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Weiner et al. (2005) studied this question.
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