Cut to the chase: A ruthenium complex derived from 1-adamantyl carboxylate (1-AdCO2−) enabled highly regioselective intermolecular direct alkylation of arenes with unactivated primary and secondary alkyl halides bearing β-hydrogen atoms (see scheme; NMP=N-methylpyrrolidinone).
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Ackermann et al. (2009) studied this question.
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