In Brief Study Design. The authors present a case of cauda equina compression after laminotomy and discectomy where incidental durotomy was managed with the application of hydrogel sealant. The patient reported return of radicular symptoms on the first postoperative day, and deterioration to early cauda equina syndrome after bending on the sixth day. Objective. To demonstrate that in addition to its recognized volume expansion properties, that the product has the ability to migrate and produce symptoms remote from where it was inserted. Summary of Background Data. The physical properties of DuraSeal (Confluent Surgical, Waltham, MA), a hydrogel dural sealant, make it an effective adjunct to dural closure. Its volume expansion has been associated with neural compression after posterior fossa decompression. We have found no reported migration of this product. Methods. Sequential postoperative imaging shows swelling and migration of the hydrogel into spinal canal with resultant compression. Exploration on postoperative day 10 revealed sealant causing cauda equina compression proximal to the site of the durotomy. Conclusion. The authors recommend that in addition to caution regarding its potential mass effect, that cognizance be taken of the product’s potential to migrate and result in symptoms at a distant site. A case report of symptomatic cauda equina compression due to DuraSeal hydrogel dural sealant after laminotomy and discectomy. Postoperative imaging confirms swelling and migration of sealant into the neural canal. Material was surgically removed with relief of symptoms.
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Mulder et al. (2009) studied this question.
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