PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
September 4, 1980New England Journal of Medicine278 citations

Transplantation of Marrow from an Unrelated Donor to a Patient with Acute Leukemia

View Full Paper
JHJohn A. HansenRCReginald A. CliftETE. Donnall Thomas

Key Points

Key points are not available for this paper at this time.

Abstract

MARROW transplantation between genotypically HLA-identical siblings has an established and expanding place in the management of leukemia and aplastic anemia.1 2 3 The majority of patients, unfortunately, do not have such siblings. Experience with marrow donors other than HLA-identical siblings has been limited. Recently it has been demonstrated that for patients with acute leukemia, marrow transplantation performed during remission improves the probability of disease-free survival.1 , 2 , 4 , 5 In view of this new therapeutic outlook, the determination of new criteria for donor selection has become clinically relevant. We report here a successful marrow transplantation in a patient with acute lymphoblastic leukemia in second remission; the . . .

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Hansen et al. (1980) studied this question.

synapsesocial.com/papers/6a628416ce9bb37a6d7dd7a6https://doi.org/10.1056/nejm198009043031007
Ask AI
Helpful
Bookmark
Share
View Full Paper