Key result
Hyperglycaemia and selective insulin resistance of the vasculature are proposed as key mechanisms responsible for the increased incidence of hypertension and cardiovascular disease in diabetes.
Why the study?
How do hyperglycaemia and hyperinsulinaemia contribute to vascular dysfunction, hypertension, and cardiovascular disease in diabetes?
Design
Review
Authors
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May guide vascular insulin pathway research in diabetes; should not yet change clinical practice.
Hyperglycaemia and selective insulin resistance in the vasculature are proposed as key mechanistic drivers of hypertension and cardiovascular disease in patients with diabetes.
G L King (1996) conducted a review in Diabetes and vascular dysfunction. Hyperglycaemia and hyperinsulinaemia was evaluated. Hyperglycaemia and selective insulin resistance of the vasculature are proposed as key mechanisms responsible for the increased incidence of hypertension and cardiovascular disease in diabetes.
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