Key result
Pre-ablation microspirometry screening identifies airflow limitation in ~20% of AF patients.
Why the study?
Although COPD is a recognized risk factor for AF and negatively impacts rhythm control treatments, practical guidance on how and when to screen for COPD is lacking.
Does an integrated screening pathway using handheld microspirometry feasibly identify underlying chronic obstructive pulmonary disease in patients with atrial fibrillation accepted for catheter ablation?
Observational (n=232)
No
Does an integrated screening pathway using handheld microspirometry feasibly identify underlying chronic obstructive pulmonary disease in patients with atrial fibrillation accepted for catheter ablation?
Integrating a handheld microspirometry screening pathway into a pre-ablation AF clinic is highly feasible and successfully uncovers unrecognized airflow limitation in a significant proportion of patients.
AIMS: Chronic obstructive pulmonary disease (COPD) negatively impacts the efficacy of heart rhythm control treatments in patients with atrial fibrillation (AF). Although COPD is recognized as a risk factor for AF, practical guidance about how and when to screen for COPD is not available. Herein, we describe the implementation of an integrated screening and management pathway for COPD into the existing pre-ablation work-up in an AF outpatient clinic infrastructure. METHODS AND RESULTS: Consecutive unselected patients accepted for AF catheter ablation in the Maastricht University Medical Center+ were prospectively screened for airflow limitation using handheld (micro)spirometry at the pre-ablation outpatient clinic supervised by an AF nurse. Patients with results suggestive of airflow limitation were offered referral to the pulmonologist. Handheld (micro)spirometry was performed in 232 AF patients, which provided interpretable results in 206 (88.8%) patients. Airflow limitation was observed in 47 patients (20.3%). Out of these 47 patients, 29 (62%) opted for referral to the pulmonologist. The primary reason for non-referral was low perceived symptom burden. Using this screening strategy 17 (out of 232; 7.3%) ultimately received a diagnosis of chronic respiratory disease, either COPD or asthma. CONCLUSION: A COPD care pathway can successfully be embedded in an existing AF outpatient clinic infrastructure, using (micro)spirometry and remote analysis of results. Although one out of five patients had results suggestive of an underlying chronic respiratory disease, only 62% of these patients opted for a referral. Pre-selection of patients as well as patient education might increase the diagnostic yield and requires further research.
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Velden et al. (2023) conducted an observational in Atrial Fibrillation (n=232). COPD screening with handheld (micro)spirometry was evaluated on Percentage of patients with airflow limitation identified using single (micro)spirometry. Implementation of a pre-ablation screening pathway using handheld microspirometry was feasible in 88.8% of patients and successfully identified airflow limitation in 20.3% of patients with atrial fibrillation.
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