Key result
Colchicine treatment for 30 days was evaluated for its anti-inflammatory potential using targeted proteomics in patients with chronic coronary artery disease.
Why the study?
Although COLCOT showed cardiovascular benefit with colchicine, its effect in human atherosclerosis remained unclear.
Does colchicine treatment for 30 days improve anti-inflammatory profiles in patients with chronic coronary artery disease?
Observational
Does colchicine treatment for 30 days improve anti-inflammatory profiles in patients with chronic coronary artery disease?
This study evaluates the mechanistic anti-inflammatory effects of 30-day colchicine therapy in patients with chronic coronary artery disease using targeted proteomics.
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Hypothesis-generating for colchicine anti-inflammatory effects in CAD; leaves open clinical outcome impact pending randomized trials.
Opstal et al. (2020) conducted an observational in chronic coronary artery disease. Colchicine vs. Baseline (before treatment) was evaluated on Anti-inflammatory potential assessed via targeted proteomics. Colchicine treatment for 30 days was evaluated for its anti-inflammatory potential using targeted proteomics in patients with chronic coronary artery disease.
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