What question did this study set out to answer?

The aim is to compare the cerebrovascular anatomy of C57Black/6 and SV129 mice.

Differences in the cerebrovascular anatomy of C57Black/6 and SV129 mice

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Randomized trial uncovers cerebrovascular differences in C57Black/6 and SV129 mice, suggesting caution in stroke research implications.

The aim is to compare the cerebrovascular anatomy of C57Black/6 and SV129 mice.
Microvascular injection of carbon black stained latex was performed to visualize vascular architecture.
Dorsal brain surface was photographed to assess the number, diameter, and position of pial anastomotic vessels.
No significant difference in the mean number and diameter of anastomoses between the strains was found.
C57Black/6 mice displayed anastomoses significantly closer to the midline, suggesting a larger vascular territory of the middle cerebral artery.
C57Black/6 mice showed a larger infarct volume compared to SV129 mice, raising concerns for stroke research.

Maeda et al. (1998) studied this question.

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