Key result
New-onset postoperative arrhythmia occurred in 4.8% of patients after lower gastrointestinal surgery and was independently associated with significantly higher in-house mortality (OR 3.37) and organ failure.
Why the study?
Postoperative arrhythmia after lower gastrointestinal surgery has been rarely investigated and only rudimentarily described.
What is the incidence and clinical impact of new-onset postoperative arrhythmia after lower gastrointestinal tract surgery?
Cohort (n=1,171)
No
What is the incidence and clinical impact of new-onset postoperative arrhythmia after lower gastrointestinal tract surgery?
New-onset postoperative arrhythmia after lower gastrointestinal surgery is relatively uncommon (4.8%) but is associated with significantly increased risks of organ failure and in-house mortality.
Identifies a high-risk phenotype requiring vigilant monitoring after lower GI surgery; leaves open whether.
Postoperative arrhythmias (PAs) are common events and have been widely investigated in cardiothoracic surgery. Within visceral surgery, a recent study revealed a significant occurrence of PA in esophageal resections. In contrast, PA in lower gastrointestinal surgery is rarely investigated and has been rudimentary described in the medical literature. The present work is a retrospective cohort study of 1171 patients who underwent surgery of lower gastrointestinal tract between 2012 and 2018. All included patients were treated and monitored in the intensive care unit (ICU) or intermediate care unit (IMC) after surgery. Follow-up, performed between January and May 2021, was obtained for the patients with PA investigating the possible persistence of PA and complications such as permanent arrhythmia or thromboembolic events after discharge. In total, n = 1171 patients (559 female, 612 male) without any history of prior arrhythmia were analyzed. Overall, PA occurred in n = 56 (4.8%) patients after surgery of the lower GI. The highest incidence of PA was seen in patients undergoing bowel surgery after mesenteric ischaemia (26.92%), followed by cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC; 16.67%). PA was significantly associated with higher age (72 years (IQR 63-78 years) vs. 64 years (IQR 55-73.5 years), p < 0.001) and longer length of stay in the ICU (median 15 days (IQR 5-25 days) vs. median 2 days (IQR 1-5 days), p < 0.001). PA was independently associated with organ failure (OR = 4.62, 95% CI 2.11-10.11, p < 0.001) and higher in-house mortality (OR = 3.37, 95% CI 1.23-9.28, p < 0.001). In median, PA occurred 66.5 h after surgery. In follow-up, 31% of all the patients with PA showed development of permanent arrhythmia. The incidence of PA after lower GI surgery is comparatively low. Its occurrence, however, seems to have severe implications since it is significantly associated with higher rates of organ failure and in-house mortality. Also, compared to the general population, the development of permanent arrhythmia is significantly higher in patients who developed new-onset PA.
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Rühlmann et al. (2023) conducted a cohort in Surgery of the lower gastrointestinal tract (n=1,171). New-onset postoperative arrhythmia vs. No postoperative arrhythmia was evaluated on In-house mortality (OR 3.37, 95% CI 1.23-9.28, p=<0.001). New-onset postoperative arrhythmia occurred in 4.8% of patients after lower gastrointestinal surgery and was independently associated with significantly higher in-house mortality (OR 3.37) and organ failure.
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