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Angiotensin peptides may act as neurotransmitters and are hypothesized to be synthesized intracellularly within neurons to regulate physiological processes in the brain.
This review hypothesizes that angiotensin peptides may be synthesized intracellularly in neurons, acting as neurotransmitters.
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Hypothesis of intracellular neuronal angiotensin synthesis remains unproven; leaves open its role in central cardiovascular regulation.
The renin-angiotensin system in the brain acts to regulate a number of physiological processes. Evidence suggests that angiotensin peptides may act as neurotransmitters, although their biosynthetic pathways are poorly understood. We review evidence for neuronal production of angiotensin peptides and hypothesize that angiotensin may be synthesized intracellularly in neurons.
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Grobe et al. (2008) studied this question. Angiotensin peptides may act as neurotransmitters and are hypothesized to be synthesized intracellularly within neurons to regulate physiological processes in the brain.
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