PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
July 1, 1987Journal of Gerontology

The Effect of Age on Hemodynamic Response to Graded Postural Stress in Normal Men

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does age affect the hemodynamic response to graded postural stress in healthy men?

Population

Healthy men in three age groups: young, middle-aged, and older.

Comparison

Graded gravity increments from 10 degrees… vs Comparison across the three age groups

Design

Cross-sectional

Key result

Older men (60-69 years) exhibited significantly lesser increases in heart rate and diastolic pressure in response to graded postural stress compared to younger men.

Authors

JSJames J. SmithCHC. V. HughesMPMichael J. Ptacin

Discussion

Loading...

Member takes

Overview

Attenuated HR and diastolic pressure responses to head-up tilt in older men suggest reduced orthostatic compensation; leaves open relevance to syncope risk in aging.

Study Design

Type

Observational

Structured PICO

Does age affect the hemodynamic response to graded postural stress in healthy men?

P
Population
Healthy men in young (20-29 years), middle-aged (40-49 years), and older (60-69 years) groups evaluated for hemodynamic responses to graded postural stress.
E
Exposure
Graded gravity (g) increments from 10 degrees headdown (-0.17 g) to 70 degrees headup (+0.94 g) tilt
C
Comparator
Comparison across the three age groups (young vs. middle-aged vs. older)
O
Outcome
Hemodynamic effects including thoracic blood volume, ventricular stroke volume, heart rate, and diastolic pressuresurrogate

Older men exhibit blunted heart rate and diastolic pressure responses to postural stress, providing a physiological mechanism for the increased incidence of postural hypotension in the elderly.

Cite This Study

Smith et al. (1987) conducted an observational in Healthy. Older age (60-69 years) vs. Younger age (20-29 and 40-49 years) was evaluated on Hemodynamic response (heart rate and diastolic pressure). Older men (60-69 years) exhibited significantly lesser increases in heart rate and diastolic pressure in response to graded postural stress compared to younger men.

synapsesocial.com/papers/6a62f031cd7899abd6b6ddc6https://doi.org/10.1093/geronj/42.4.406
View Full Paper
Ask AI
Bookmark
Share