Case report shows misdiagnosed bullous mastocytosis in a child, highlighting the need for early skin biopsy.
A 2.5-year-old boy presented with generalized pruritic bullae misdiagnosed as allergic dermatitis for two years. Histopathology with Giemsa stain confirmed mast cell infiltration, establishing a diagnosis of bullous mastocytosis. This case highlights the importance of early skin biopsy with special stains in children with chronic bullous eruptions and negative autoimmune serology.
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Wang et al. (2026) studied this question.
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