Key result
Imaging-guided valve-sparing pacing proves safe in 3 patients with prior tricuspid TEER without worsening TR.
Why the study?
Permanent pacing after tricuspid TEER is technically challenging due to risk of interaction between pacing systems and repair devices, with limited guiding evidence.
Are multimodality imaging-guided valve-sparing pacing strategies safe and feasible in patients with prior tricuspid TEER?
Case Report (n=3)
No
Are multimodality imaging-guided valve-sparing pacing strategies safe and feasible in patients with prior tricuspid TEER?
Imaging-guided valve-sparing pacing strategies, including leadless pacemakers and conduction system pacing, are feasible and safe in patients with prior tricuspid TEER.
LBBAP may aid LVEF recovery post-tricuspid TEER pacing; leaves open prospective confirmation of safety and efficacy.
BACKGROUND: Permanent pacing after tricuspid transcatheter edge-to-edge repair (TEER) may be technically challenging due to the risk of interaction between pacing systems and repair devices. Evidence guiding optimal pacing strategies in this setting remains limited. METHODS: We report a single-center case series of three patients with previous tricuspid TEER who required permanent pacing. Device selection and procedural planning were guided by multimodality imaging, including transesophageal echocardiography (TEE) and intracardiac echocardiography (ICE). Valve-sparing pacing strategies were selected according to individual clinical characteristics. RESULTS: Two elderly patients underwent implantation of a leadless pacemaker, while a third patient with dilated cardiomyopathy underwent left bundle branch area pacing (LBBAP) during cardiac resynchronization therapy upgrade. Imaging guidance allowed safe traversal of the repaired tricuspid valve while avoiding mechanical interaction with the TEER devices. All procedures were successful, with stable pacing parameters and no procedural complications. Tricuspid regurgitation remained unchanged in all patients during follow-up. In the patient undergoing LBBAP, left ventricular ejection fraction improved from 30% to 57% at 6 months. CONCLUSIONS: Valve-sparing pacing strategies guided by multimodality imaging appear feasible and safe in patients with prior tricuspid TEER. Leadless pacemakers and conduction system pacing represent complementary options that can be tailored to individual clinical profiles.
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Azañón-Cantero et al. (2026) conducted a case report in Previous tricuspid transcatheter edge-to-edge repair (TEER) requiring permanent pacing (n=3). Valve-sparing pacing strategies guided by multimodality imaging was evaluated on Procedural success and complications. Imaging-guided valve-sparing pacing strategies were successfully and safely performed in 3 patients with prior tricuspid TEER, with no procedural complications and unchanged tricuspid regurgitation.
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