Key result
A higher systemic immune-inflammation index independently predicted an increased risk of in-hospital bleeding complications in STEMI patients undergoing primary percutaneous coronary intervention (OR 1.163).
Why the study?
To investigate the relationship between the systemic immune-inflammation index and bleeding complications in STEMI after pPCI.
Does the systemic immune-inflammation index (SII) predict bleeding complications in STEMI patients undergoing pPCI?
Cohort (n=1,778)
No
Does the systemic immune-inflammation index (SII) predict bleeding complications in STEMI patients undergoing pPCI?
The systemic immune-inflammation index (SII) is a significant independent predictor of bleeding complications in STEMI patients undergoing primary PCI.
SII may aid bleeding risk assessment post-pPCI in STEMI; leaves open incremental value beyond CRUSADE score in prospective validation.
Objectives:To investigate the relationship between the systemic immune-inflammation index (SII) and bleeding complications in ST-elevated myocardial infarction (STEMI) after percutaneous coronary intervention (pPCI). Materials and Methods:This retrospective study included 1778 patients who presented with STEMI and underwent pPCI.Patients were divided into two groups: those who developed bleeding and those who did not.The SII values and CRUSADE bleeding score were calculated. Results:In the group with bleeding complications, the ages were 62 (50-73), and 69.6% were male.Multivariate analysis identified age 1.031(1.015-1.048)-p<0.001,basal creatinine 1.789 (1.366-2.342)-p<0.001,SII 1.163 (1.028-1.315)-p=0.013as significant predictors of bleeding complications. Conclusion:The easily calculated SII may help predict bleeding complications in STEMI patients undergoing pPCI.
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Kalkan et al. (2024) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=1,778). Systemic immune-inflammation index (SII) vs. Lower systemic immune-inflammation index was evaluated on In-hospital bleeding complications (OR 1.163, 95% CI 1.028-1.315, p=0.013). A higher systemic immune-inflammation index independently predicted an increased risk of in-hospital bleeding complications in STEMI patients undergoing primary percutaneous coronary intervention (OR 1.163).
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