Endolymphatic space imaging in idiopathic sudden sensorineural hearing loss with vertigo

OBJECTIVES/HYPOTHESIS: To investigate endolymphatic space images in patients with idiopathic sudden sensorineural hearing loss (ISNHL) and vertigo using three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI). STUDY DESIGN: This is a prospective study of an analysis using the imaging technology of 3D-FLAIR MRI for patients with ISNHL and vertigo. METHODS: 3D-FLAIR MRI was performed 24 hours after intratympanic injection of gadolinium-diethylenetriamine penta-acetic acid. RESULTS: In four of seven cases of ISNHL with vertigo, endolymphatic hydrops were confirmed in the cochlea and/or the vestibule of the affected ears. CONCLUSIONS: The results of the study imply that there may be some relationship between endolymphatic hydrops and ISNHL with vertigo.