Novel route synthesizes polysubstituted pyridine derivatives, indicating efficient catalytic properties.
We report an efficient novel route for the synthesis of polysubstituted pyridine derivatives with DBU-SiO2 catalyzed one-pot four-component reaction. This protocol offers a mild condition that which affords a series of new polysubstituted pyridine derivatives with good yields. A plausible mechanism for this process is proposed.
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Yakkanti et al. (2023) studied this question.
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