Why the study?
Does myocardial injury after noncardiac surgery (MINS) predict 30-day mortality in adults aged 45 years or older undergoing in-patient noncardiac surgery?
Population
15,065 patients aged 45 years or older who underwent in-patient noncardiac surgery, international cohort.
Comparison
Myocardial injury after noncardiac surgery… vs Patients without MINS.
Design
Cohort
Follow-up
30 days
Key result
Myocardial injury after noncardiac surgery (MINS) occurred in 8.0% of patients and independently predicted 30-day mortality (adjusted HR 3.87; 95% CI 2.96-5.08).
Authors
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MINS detection aids postoperative risk stratification; leaves open whether targeted interventions improve outcomes in this observational cohort.
Cohort (n=15,065)
Yes
Does myocardial injury after noncardiac surgery (MINS) predict 30-day mortality in adults aged 45 years or older undergoing in-patient noncardiac surgery?
Hazard Ratio: 3.87 (95% CI 2.96–5.08)
MINS is a common complication (8.0%) after noncardiac surgery that often lacks ischemic symptoms but strongly predicts 30-day mortality.
Botto et al. (2014) conducted a cohort in In-patient noncardiac surgery (n=15,065). Myocardial injury after noncardiac surgery (MINS) vs. No MINS was evaluated on 30-day mortality (adjusted HR 3.87, 95% CI 2.96-5.08). Myocardial injury after noncardiac surgery (MINS) occurred in 8.0% of patients and independently predicted 30-day mortality (adjusted HR 3.87; 95% CI 2.96-5.08).