Key result
Recent COVID-19 recovery is linked to abnormal right ventricular strain in ~52% of patients.
Why the study?
While pulmonary complications of COVID-19 received substantial focus, this study aimed to evaluate cardiac changes and assess right ventricular function using modalities like 2D echocardiography in recovered COVID-19 patients.
Does prior COVID-19 infection affect right ventricular function and the incidence of arrhythmias in recovered patients?
Observational (n=139)
No
Does prior COVID-19 infection affect right ventricular function and the incidence of arrhythmias in recovered patients?
A significant proportion of patients recently recovered from COVID-19 demonstrate subclinical right ventricular dysfunction and an increased incidence of arrhythmias.
Hypothesis-generating for subclinical post-COVID RV dysfunction; larger controlled studies needed before guiding surveillance.
The COVID-19 caused by novel single-stranded RNA enveloped severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) first appeared in Wuhan, China. A lot of focus has been given to pulmonary complications. According to several case reports, cardiovascular associated clinical manifestations include myocarditis, arrhythmias, veno-thromboembolic events, acute coronary syndrome (ACS), and pericarditis. Different modalities in diagnosis like 2D, doppler can help in the early diagnosis of right ventricular function. This study evaluates the cardiac changes in recovered COVID-19 positive patients by 2D echocardiogram and other modalities. In this prospective observational study, 139 participants recently recovered from COVID-19 illness were identified and recruited after obtaining the Informed concerned form (ICF). The patients once enrolled were subjected to 2D echo and ECG as part of routine clinical practice. Out of 139 patients, 89 (64.03%) were males, and the rest were females. Based on the severity scale, 13 (9.35%) participants had suffered a severe form of COVID-19 infection. Right ventricular functional assessment, right ventricular global strain (RVGLS) was abnormal in 72 (51.80%) participants. Arrhythmias were reported in 31 (22.30%) participants; among them, 30 participants had sinus bradycardia. Our study demonstrates the association between COVID-19 and cardiac changes/ incidence of cardiovascular complications in recovered COVID-19 patients. This study provides first-hand evidence of the incidence of abnormal LVGLS and RVGLS in COVID-19 recovered patients. In addition, there was a higher incidence of arrythmias.
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Ritesh Khandelwal (2021) conducted an observational in Recovered COVID-19 (n=139). COVID-19 infection was evaluated on Abnormal right ventricular global longitudinal strain (RVGLS). In a cohort of 139 patients recently recovered from COVID-19, 51.8% exhibited abnormal right ventricular global strain and 22.3% had documented arrhythmias.
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