Key result
Water-perfused high-resolution manometry showed moderate to good agreement with solid-state HRM (e.g., ICC 0.90 for distal contractile integral), with only small differences in outcome measures.
Why the study?
Does water-perfused HRM show acceptable agreement with solid-state HRM in healthy volunteers?
Population
50 healthy volunteers (mean age 35 yr, range 21-64 yr; 15 women, 35 men)
Comparison
Water-perfused high-resolution manometry (HRM) vs Solid-state HRM
Design
Cross-sectional, randomized order of tests
Authors
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May support water-perfused HRM adoption; leaves open validation in symptomatic patients.
RCT (n=50)
Randomized order (crossover)
Does water-perfused HRM show acceptable agreement with solid-state HRM in healthy volunteers?
Effect estimate: ICC 0.39 to 0.90
Water-perfused HRM yields normal values comparable to solid-state HRM with moderate to good agreement, validating its use for esophageal manometry.
Kessing et al. (2014) conducted an RCT in Healthy volunteers (n=50). Water-perfused high-resolution manometry (HRM) vs. Solid-state HRM was evaluated on Agreement between water-perfused and solid-state HRM (assessed via intraclass correlation coefficient) (ICC 0.39 to 0.90). Water-perfused high-resolution manometry showed moderate to good agreement with solid-state HRM (e.g., ICC 0.90 for distal contractile integral), with only small differences in outcome measures.
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