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Summary Advanced testicular cancer is a rare but curable condition. Cisplatin-based combination chemotherapy achieves high cure rates and may be combined with surgery and/or radiotherapy in selected cases. Prognosis varies according to international prognostic criteria. De-escalation of therapy may be appropriate in those with good prognosis disease aiming to lessen long-term treatment related side effects. Conversely, escalation of therapy should be considered in those with poor prognosis disease prompted by review of tumor marker decline following initiation of chemotherapy. Long term survivorship outcomes are important and are best achieved through establishing dedicated holistic survivorship programs.
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Gilson et al. (2024) studied this question.
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